Research & clinical trials

Advancing surgical oncology

Translating research into better outcomes in peritoneal disease and sarcoma — rare diseases that demand their own evidence.

Active research areas

Lines of work

Peritoneal Surface Malignancies

  • Prognostic factors in CRS+HIPEC for colorectal metastases
  • Novel HIPEC drug regimens
  • Quality-of-life outcomes after cytoreductive surgery
  • Patient selection and PCI optimisation

Retroperitoneal Sarcoma

  • Compartmental resection outcomes
  • Neoadjuvant strategies
  • Recurrence patterns and management
  • International collaborative registries
  • Lead author of the first ERAS consensus for primary retroperitoneal sarcoma surgery (Hispano-Luso consensus)

Pseudomyxoma Peritonei

  • Classification and prognosis of appendiceal pseudomyxoma
  • Long-term follow-up after complete cytoreduction
  • Role of HIPEC in low- and high-grade disease

Nephroprotection During HIPEC

  • Prevention of cisplatin-HIPEC nephrotoxicity
  • Cilastatin vs thiosulfate comparative study
  • Renal protection biomarker monitoring

Clinical trials

Ongoing studies

Recruiting

Cilastatin vs thiosulfate: nephroprotection in CRS+HIPEC with cisplatin

A prospective study evaluating nephroprotection with cilastatin versus sodium thiosulfate in patients undergoing CRS+HIPEC with cisplatin.

International collaboration

A global network in peritoneal oncology

Peritoneal carcinomatosis is uncommon in any single centre. No hospital accrues enough cases on its own to answer the questions that matter, which is why this work is done as a network.

Beijing · July 2026

International Research Center for Peritoneal Surface Oncology

School of Clinical Medicine, Tsinghua University

Took part in the academic exchange programme behind the creation of the IRCPSO, bringing together teams from China, Japan, the Netherlands, Spain and India around one goal: advancing the treatment of peritoneal carcinomatosis.

Live-broadcast cytoreductive procedures, multicentre projects and a proposed worldwide registry for diffuse malignant peritoneal mesothelioma.

Ongoing exchange

Beijing Tsinghua Changgung Hospital

Tsinghua University · Beijing, China

Academic and surgical exchange with the BTCH team and in Harbin: joint operating sessions and shared techniques for the treatment of peritoneal surface malignancy.

The link with Tsinghua is the foundation on which the IRCPSO involvement was built.

Publications

Peer-reviewed work

50 publications

  1. 2026·Cirugía EspañolaSarcoma

    ¿Estamos tratando bien el tumor desmoide en España? Resultados de la primera encuesta nacional

  2. 2026·Annals of Surgical OncologySarcoma

    ASO Author Reflections: Enhanced Recovery in Retroperitoneal Sarcoma Surgery — From Concept to Consensus

  3. 2026·Annals of Surgical OncologyPeritoneal

    ASO Visual Abstract: Protective Effect of Diuresis During Hyperthermia on Acute Kidney Injury in Cytoreductive Surgery with HIPEC

  4. 2026·Annals of Surgical OncologySarcoma

    Consensus Guidelines on Perioperative Care in Primary Retroperitoneal Sarcoma Surgery

  5. 2026·Cirugía EspañolaSarcoma

    Cuidados perioperatorios en la cirugía del sarcoma retroperitoneal primario: una encuesta hispano-lusa sobre prácticas actuales

  6. 2026·CancersSarcoma

    Experience of a Referral Center with Desmoid Tumors, Part 2: A Retrospective Analysis of 109 Cases

  7. 2026·Clinical and Translational OncologyPeritoneal

    Pressurised intraperitoneal aerosol chemotherapy (PIPAC) for peritoneal metastases: a scoping review of clinical evidence across emerging indications

  8. 2026·Annals of Surgical OncologyPeritoneal

    Protective Effect of Diuresis During Hyperthermia on Acute Kidney Injury in Cytoreductive Surgery with HIPEC

  9. 2026·CancersSarcoma

    Surgical Management and Therapeutic Strategy of Uterine Sarcoma According to Histological Subtype and Staging: Updated Review and Recommendations

  10. 2025·CancersSarcoma

    Desmoid Tumors — Experience from a Referral Center, Part 1: Multidisciplinary Review and Practical Recommendations

  11. 2025·CancersSarcoma

    Diagnostic Delay in Soft Tissue Sarcomas: A Review

  12. 2025·CancersSarcoma

    Ibero-American Consensus for the Management of Liver Metastases of Soft Tissue Sarcoma: Updated Review and Clinical Recommendations

  13. 2023·CancersPeritoneal

    Appendiceal Mucinous Neoplasms: From Clinic to Pathology and Prognosis

  14. 2023·European Journal of Surgical OncologyPeritoneal

    External multicentre validation of pseudomyxoma peritonei PSOGI-Ki67 classification

  15. 2023·CancersSarcoma

    Updated Review and Clinical Recommendations for the Diagnosis and Treatment of Patients with Retroperitoneal Sarcoma by the Spanish Sarcoma Research Group (GEIS)

  16. 2022·Annals of Surgical OncologyPeritoneal

    ASO Author Reflections: Predicting Prognosis in Patients with Pseudomyxoma

  17. 2022·Cirugía y CirujanosOther

    Mecanismos del precondicionamiento regenerativo en hepatectomías subtotales en modelo porcino

  18. 2022·Annals of Hepato-Biliary-Pancreatic SurgeryOther

    Neoadjuvant therapy impact in early pancreatic cancer: bioborderline vs. non-bioborderline

  19. 2022·Annals of Surgical OncologyPeritoneal

    Validation of a Nomogram to Predict Recurrence in Patients with Mucinous Neoplasms of the Appendix with Peritoneal Dissemination After CRS and HIPEC

  20. 2021·Annals of Hepato-Biliary-Pancreatic SurgeryOther

    Advances in neoadjuvant therapy for resectable pancreatic cancer over the past two decades

  21. 2021·British Journal of SurgeryOther

    Death following pulmonary complications of surgery before and during the SARS-CoV-2 pandemic

  22. 2021·BJS OpenPeritoneal

    Defining stage in mucinous tumours of the appendix with peritoneal dissemination: the importance of grading terminology: systematic review

  23. 2021·Annals of Case ReportsSarcoma

    Dermatofibrosarcoma Protuberans (DFSP) with Fibrosarcomatous Transformation: A Case Report

  24. 2021·International Journal of Molecular SciencesPeritoneal

    Effect of Cilastatin on Cisplatin-Induced Nephrotoxicity in Patients Undergoing Hyperthermic Intraperitoneal Chemotherapy

  25. 2021·The Lancet OncologyOther

    Effect of COVID-19 pandemic lockdowns on planned cancer surgery for 15 tumour types in 61 countries: an international, prospective, cohort study

  26. 2021·British Journal of SurgeryOther

    SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study

  27. 2021·AnaesthesiaOther

    Timing of surgery following SARS‐CoV‐2 infection: an international prospective cohort study

  28. 2021·Journal of Clinical PathologyPeritoneal

    Which classification system defines best prognosis of mucinous neoplasms of the appendix with peritoneal dissemination: TNM vs PSOGI?

  29. 2020·American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant SurgeonsOther

    Bariatric surgery and transplantation: A bridge not so far.

  30. 2020·The British journal of surgeryOther

    Delaying surgery for patients with a previous SARS-CoV-2 infection.

  31. 2020·Journal of clinical oncology : official journal of the American Society of Clinical OncologyOther

    Elective Cancer Surgery in COVID-19-Free Surgical Pathways During the SARS-CoV-2 Pandemic: An International, Multicenter, Comparative Cohort Study.

  32. 2020·The British journal of surgeryOther

    Elective surgery cancellations due to the COVID-19 pandemic: global predictive modelling to inform surgical recovery plans.

  33. 2020·Transplantation ProceedingsOther

    Evaluation of Plasma Disappearance Rate Indocyanine Green Clearance as a Predictor of Liver Graft Rejection in Donor Brain Death

  34. 2020·The British journal of surgeryOther

    Global guidance for surgical care during the COVID-19 pandemic.

  35. 2020·CancerOther

    Head and neck cancer surgery during the COVID-19 pandemic: An international, multicenter, observational cohort study.

  36. 2020·The British journal of surgeryOther

    Impact of asymptomatic COVID-19 patients in global surgical practice during the COVID-19 pandemic.

  37. 2020·Lancet (London, England)Other

    Mortality and pulmonary complications in patients undergoing surgery with perioperative SARS-CoV-2 infection: an international cohort study.

  38. 2020·Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and IrelandOther

    Outcomes from elective colorectal cancer surgery during the SARS-CoV-2 pandemic.

  39. 2020·Journal of Global HealthOther

    Screening policies, preventive measures and in-hospital infection of COVID-19 in global surgical practices

  40. 2020·British Journal of SurgeryOther

    Surgeons' fear of getting infected by COVID19: A global survey

  41. 2019·Journal of Gastrointestinal SurgeryOther

    Comprehensive Characterization of a Porcine Model of The “Small-for-Flow” Syndrome

  42. 2019·Transplantation ProceedingsOther

    Donor Risk Index Has an Impact in Intraoperative Measure of Hepatic Artery Flow and in Clearance of Indocyanine Green: An Observational Cohort Study

  43. 2019·World journal of hepatologyOther

    Hepatic flow is an intraoperative predictor of early allograft dysfunction in whole-graft deceased donor liver transplantation: An observational cohort study.

  44. 2019·Archives of Organ TransplantationOther

    Purpose of the measurement of intraoperative hepatic hemodynamics in liver transplant surgery

  45. 2019·Surgery: Current Trends and InnovationsSarcoma

    Radiation-Induced Intrapelvic Osteosarcoma Treated with Radical Pelvic Surgery: Case Report and Literature Review

  46. 2018·Current Transplantation ReportsOther

    DCD Liver Transplant: a Meta-review of the Evidence and Current Optimization Strategies

  47. 2018·The Spine JournalSarcoma

    Role of intraoperative radiotherapy in the treatment of sacral chordoma

  48. 2017·SurgeryOther

    Preconditioning by portal vein embolization modulates hepatic hemodynamics and improves liver function in pigs with extended hepatectomy

  49. 2016·Cirugía EspañolaOther

    Linfoma adrenal primario; una entidad poco frecuente en el diagnóstico diferencial de las tumoraciones suprarrenales

  50. 2013·Journal of Liver: Disease & TransplantationOther

    Early Changes in Small-for-Flow Syndrome: An Experimental Model

View the full publication list on ORCID ↗

Interested in collaboration?

Open to research collaborations in peritoneal oncology and sarcoma.